Morphological and functional alteration of erythrocyte ghosts and giant unilamellar vesicles caused by Vipera latifi venom.

National Academy of Sciences of Ra L.a. Orbeli Institute of Physiology Maryam Mohamadvarzi Morphological and Functional Alteration of Erythrocyte Ghosts and Giant Unilamellar Vesicles Caused by Montivipera Latifi Venom

Electroformation of giant unilamellar vesicles from erythrocyte membranes under low-salt conditions.

Giant unilamellar vesicles (GUVs) are an attractive experimental model for studying various membrane-related phenomena. The procedure for GUV electroformation from erythrocyte ghosts under physiological conditions was introduced recently; however, it allows preparation of a limited number of GUVs. Here we describe an efficient, reliable, and simple method for electroformation of GUVs from nativ...

Cytotoxic Effect of Iranian Vipera Lebetina snake Venom on HUVEC Cells

Objective: Envenomation by heamotoxic snakes constituted a critical health occurrence in the world. Bleeding is the most sever consequence following snake bite with viperid and crothalid snakes. It is believed that the degradation of vascular membrane caused hemorrhage; in contrast, some suggested that direct cytotoxicity has role in endothelial cell disturbances. This study was to evaluate the...

Cytotoxic Effect of Iranian Vipera Lebetina snake Venom on HUVEC Cells

Objective: Envenomation by heamotoxic snakes constituted a critical health occurrence in the world. Bleeding is the most sever consequence following snake bite with viperid and crothalid snakes. It is believed that the degradation of vascular membrane caused hemorrhage; in contrast, some suggested that direct cytotoxicity has role in endothelial cell disturbances. This study was to evaluate the...

Purified Lesser weever fish venom (Trachinus vipera) induces eryptosis, apoptosis and cell cycle arrest

Accidents caused by the sting of Trachinus vipera (known as Lesser weever fish) are relatively common in shallow waters of the Mediterranean. Symptoms after the sting vary from severe pain to edema or even tissue necrosis in some cases. Here we show that purified Lesser weever fish venom induces eryptosis, the suicidal erythrocyte death, and apoptosis of human colon carcinoma cells. The venom l...